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I was prescribed generic levo but I know my mom (longtime hypo) made me go get synthroid prescribed the next week lol GE. She said she has seen some patients that don't absorb the generic as well. Generic Levothyroxine Ericamegan My endo recommended that I take Synthroid instead of the generic. Publication types Comparative Study. Comparative Effectiveness of Persistent Use of a Name-Brand Levothyroxine (Synthroid®) vs. Synthroid: a generic Levothyroxine that may behave differently Many people wonder if levothyroxine (or levothyroxine sodium) and Synthroid are the same—and, if not, which might be better. She said she didn't realize I was on the generic, but, she wanted me on the name brand. At the time I didn't think much about it, but, when I sent my order in to mail order it cost me bucks vs. You get the same concentration of medication and such. 526)] than the Synthroid group [1. 2 out of 10 from a total of 805 ratings on Drugs. I've read that pretty much generic is plus/minus 7mcg while Synthroid would likely be plus/minus 5mcg (random numbers). T3 is about 3-4 times more powerful than T4 (depending on which study you look at) Lower-cost generic is available Ratings & Reviews Levothyroxine has an average rating of 5. To the best of my knowledge, the reason you must have your blood tested if the brand of levothyroxine you are taking changes is because there is a 5% plus or minus difference in the amount of medication absorbed between manufacturers Most generic medications are more or less the same. If Read More Created for people with ongoing healthcare needs but benefits everyone. I have been taken Levothyroxine and this last time I went to the Dr. I was feeling so crappy before starting, I didn't want to take any chances Back in 2007 the fda tightened their standards for levothyroxine since they classify it as a drug with a narrow therapeutic index. At least I have heard it several times I've read that pretty much generic is plus/minus 7mcg while Synthroid would likely be plus/minus 5mcg (random numbers). The inert ingredients vary, but that's trivial. There can be subtle differences from manufacturer to manufacturer in the actual dosage. Levothyroxine is also available under other brand names, including Tirosint® and Levoxyl® Brand vs. These results suggest that generic levothyroxine as initial therapy for mild thyroid dysfunction is as effective as brand-name levothyroxine. Except with Levothyroxine/Synthroid. She said this is one of the only drugs she really recommends not to take the generic. Persistent Use of Generic Levothyroxine on TSH Goal Achievement: A Retrospective Study Among Patients with Hypothyroidism in a Managed Care Setting. Within 3 months of filling a levothyroxine prescription, 75. Synthroid releases it's TSH over a period of 16-18 hours so when it's reaching the period where it's not in your bloodstream any more, it's time for your next morning dose. I've also read that synthroid comes from one company while generics can come from a multitude of companies. Generic: What the Research Says According to a presentation at the annual meeting of the American Association of Clinical Endocrinologists in 2017, Synthroid was associated with significantly better thyroid-stimulating hormone (TSH) lab results than generic levothyroxine. 803)] Just today, I picked up what I thought was my Synthroid refill to find out it was generic, very upset, 90 days worth, can't return it, most likely …. So the range of variability between generics and "branded" levothyroxine is minimal as far as the active ingredients. Persistent Use of Generic Levothyroxine on TSH Goal Achievement: A Retrospective Study Among Patients with Hypothyroidism in a Managed Care Setting Liya Wang, Yaozhu J. I was feeling so crappy before starting, I didn't want to take any chances GE. Brand name Synthroid and generic levothyroxine are chemically identical hormones, l-thyroxine. Conclusions: The 4 generic and brand-name levothyroxine preparations studied are different but are bioequivalent by current Food and Drug Administration criteria and are interchangeable in the majority of patients receiving thyroxine replacement therapy.. She said some drugs are fine as a generic, but, not synthroid. 10 bucks Brand-name levothyroxine was no better than generic formulations at normalizing thyrotropin levels, a new study found. I have found, and my doctor reached the same conclusion, that levothyroxine releases all of the TSH over a period of 6-8 hours, then you go 16-18 hours with no TSH. Chen, Michael Grabner, Bal Nepal, Amit Bodhani, Ramon Espaillat & James V. With most medicines, it doesn’t matter if you take the generic or brand name version or if you switch between them Conclusions and relevance: Initiation of generic vs brand-name levothyroxine formulations was associated with similar rates of normal and stable thyrotropin levels. I was prescribed generic levo but I know my mom (longtime hypo) made me go get synthroid prescribed the next week lol Synthroid vs. Using a linear mixed model, children treated with the generic LT4 had lower TSH estimated SD [1. 35 with 95% confidence interval (CI) (1. At least I have heard it several times Using the Wilcoxon rank sum test, there was no difference in TSH SD in the Synthroid group compared with the generic group (median 3. Most generic medications are more or less the same. Achieving TSH goals may provide substantial economic value by reducing hypothyroidism-related HCRU and costs. 6k views Answered >2 years ago Thank 1 thank View 1 more answer A member asked:. Synthroid and Levothyroxine are both considered T4 only thyroid medications which means that they contain the bio-identical thyroid hormone Thyroxine. Liothyronine, on the other hand, contains the most potent thyroid hormone which is known as T3 or triiodothyronine.